History and tradition
Structure
- Clinical
hematology department
- Laboratory department
"Diagnostics of blood diseases"
- Transfusion hematology
department
- Administrative department
- Quality assurance and quality control
of blood and blood products laboratory
- Department for preparation
of treatment and diagnostic plasma products
- Organization and providing
of information department of NCHT
Activities
-
Diagnostics
- Curative activities
- Preparation of blood products
- Science & research
- Clinical trials
- Educational activities
Staff
- Clinical hematology
department
- Laboratory department
"Diagnostics of blood diseases"
- Transfusion hematology department
- Administrative department
- Quality assurance and quality
control of blood and blood products laboratory
- Department for preparation of
treatment and diagnostic plasma products
- Organization and providing of
information department of NCHT
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Diagnostic
testings by Type of Testing
Kinetics of 111-In oxine and 51-Cr labelled platelets
Kinetics of 51-Cr labelled erythrocytes in peripheral blood
Volume
of circulating blood, plasma and erythrocyte masses
Kinetics of 111-In oxine labelled granulocytes
Tumour
imaging
Vitamin B-12 and folic acid
Ferritin
Erythropoietin
Beta-2 microglobulin
Thymidine
kinase
Determination of plasma viscosity.
Determination of haemopoietic stem cells in
culture.
Clinical - chemistry analysis (enzymes,
substrates, electrolytes) in serum and other
biological liquids.
Routine hematological and urine analyses.
Porphyrines (uro-, copro-, and
protoporphirine) and precursors (ALA and PBG)
in blood and urine.
Enzymes and substrates in the erythrocytes (G6PDH, PK, Glutathion
reductase, 2,3 DPG, ATP, Porphobilinogen synthase and others).
Cytological examination of bone marrow (fresh aspirated materials)
Cytological examination of bone marrow (consultation of bone marrow
smears)
Cytological examination of peripheral blood
Cytological examination of peripheral blood (consultation of blood
smears)
Examination of blood cells by cytochemical and special stains (fresh
aspirated materials and smears of bone marrow and blood)
Cytological examination of body cavity fluids and effusions
Fine
needle aspiration biopsy of lymph nodes, tumors, skin lesions
Histological examination of bone marrow biopsy (trephine biopsy)
Histological examination of fresh biopsy tissue from lymph nodes,
spleen, etc.
Histological examination of formalin - fixed biopsy materials (bone
marrow, lymph node etc.)
Histological examination of paraffin-embedded biopsy and consultation of
histological slides.
Histochemical stains of biopsy material.
Immunohistochemical examination of biopsy - bone marrow, lymph node etc.
Assessment of leukocyte surface and cytoplasmic antigens for leukaemia
and lymphoma phenotyping by flow cytometry.
Immunophenotyping
of blood cells by flow cytometry - enumeration of lymphocyte
subpopulations – CD4+ and CD8+ T-lymphocytes, NK cells, etc. in
immunodeficiency studies.
CD34+ hematopoietic progenitor cell enumeration by flow cytometry.
Assessment of leukocyte contamination of blood products by flow
cytometry.
Multi-drug resistance evaluation by flow cytometry.
Standard G-banded karyotyping
RT-PCR based detection of the specific fusion
transcripts in leukemias: BCR-ABL (P210; P190; P230); AML1-ETO;
CBFb-MYH11; PML-RARA; E2A-PBX1;
MLL-AF4; MLL-AF9; MLL-AF6; DEK-CAN; TEL-AML1; del
TAL1)
RT-PCR based evaluation of MDR1 gene
expression
RT-PCR based screening of pooled donor plasma
for Hepatitis C Virus
blood
groups typing
red cell
antigen typing
red cell
antibodies defection, identification and titration
pre-transfusion and compatibility testing
investigation of haemolytic transfusion reactions
diagnosis
and management of autoimmune haemolitic anaemias, immune- mediated blood
disorders, thrombocytopenias, acquired anaemias (PNH)
diagnosis
of drug-induced cytopenias (immune, cytotoxic)
aute-natal,
peri-natal and post-natal screening procedures and care
diagnosis, prevention and management of the haemolitic disease of newborn
LCT
Granuloaglutination tests
pre- transfusion
and compatibility testing
antibodies detection and identification
Immunochemical diagnosis of paraproteinemia
Immunochemical diagnosis of paraproteinuria in
urine
Quantitative evaluation of serum proteins /by
means of radial immunodiffusion/
- IgG, IgA, IgM
Diagnosis of cryoglobulins
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